Title: 2-Phenoxyethanol
CAS Registry Number: 122-99-6
Additional Names: 1-Hydroxy-2-phenoxyethane; ethylene glycol monophenyl ether; b-hydroxyethyl phenyl ether
Trademarks: Phenoxethol; Phenoxetol (Nipa); Phenyl Cellosolve (Union Carbide)
Molecular Formula: C8H10O2
Molecular Weight: 138.16
Percent Composition: C 69.55%, H 7.30%, O 23.16%
Line Formula: C6H5OCH2CH2OH
Literature References: Obtained by treating phenol with ethylene oxide in an alkaline medium: Becker, Barthell, Monatsh. Chem. 77, 80 (1947); see also Roithner, ibid. 15, 674, 678 (1894); Rindfusz, J. Am. Chem. Soc. 41, 669 (1919). Toxicity study: H. F. Smyth et al., J. Ind. Hyg. Toxicol. 23, 259 (1941).
Properties: Oily liquid. Faint aromatic odor. Burning taste. d2020 1.1094; d422 1.102; mp 14°; bp760 245.2°; bp80 165°; bp25 137°; bp20 128-130°. nD20 1.534. Flash pt 250°F. Soly in water: 2.67 g/100 ml. Freely sol in alcohol, ether, NaOH solns. LD50 orally in rats: 1.26 g/kg (Smyth).
Melting point: mp 14°
Boiling point: bp760 245.2°; bp80 165°; bp25 137°; bp20 128-130°
Flash point: Flash pt 250°F
Index of refraction: nD20 1.534
Density: d2020 1.1094; d422 1.102
Toxicity data: LD50 orally in rats: 1.26 g/kg (Smyth)
Derivative Type: Acetate
Molecular Formula: C10H12O3
Molecular Weight: 180.20
Percent Composition: C 66.65%, H 6.71%, O 26.64%
Properties: Liquid, bp 243°.
Boiling point: bp 243°
Use: Fixative for perfumes, in org synthesis; as bactericide in conjunction with quaternary ammonium compds; as insect repellent.
Therap-Cat: Antiseptic (topical).

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