Title:  Allantoin 
CAS Registry Number:  97-59-6 
CAS Name:  (2,5-Dioxo-4-imidazolidinyl)urea 
Additional Names:  5-ureidohydantoin;  glyoxyldiureide;  cordianine 
Molecular Formula:  C4H6N4O3 
Molecular Weight:  158.12 
Percent Composition:  C 30.38%, H 3.82%, N 35.43%, O 30.36% 
Literature References:  Product of purine metabolism.  Prepd synthetically by the oxidation of uric acid with alkaline potassium permanganate:  Org. Synth. coll. vol. II, 23 (1943).  By heating urea with dichloroacetic acid:  C. N. Zellner, J. R. Stevens, US 2158098 (1939 to Merck & Co.) Acetyl derivs:  Biltz, Loewe, J. Prakt. Chem. 141, 291 (1934).  Optically active forms have been obtained by extraction procedures. 
  
Derivative Type:  Racemic Form  
Properties:  Monoclinic plates or prisms from water, mp 238°.  One gram dissolves in 190 ml water, 500 ml alcohol; more sol in hot water and hot alcohol.  Almost insol in ether.  pH of satd water soln:  5.5. 
Melting point:  mp 238° 
  
Therap-Cat:  Vulnerary. 
Therap-Cat-Vet:  Vulnerary; debriding agent. 
Keywords:  Topical Protectant; Vulnerary.   |