Title: Ambuphylline
CAS Registry Number: 5634-34-4
CAS Name: 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione compd with 2-amino-2-methyl-1-propanol (1:1)
Additional Names: theophylline aminoisobutanol; theophylline compd with 2-amino-2-methyl-1-propanol; bufylline
Trademarks: Butaphyllamine
Molecular Formula: C11H19N5O3
Molecular Weight: 269.30
Percent Composition: C 49.06%, H 7.11%, N 26.01%, O 17.82%
Literature References: Prepn: Shelton, US 2404319 (1946 to Wm. S. Merrell). Toxicity studies: Thompson, Warren, J. Clin. Med. 31, 1337 (1946).
Properties: Crystals, mp 254-256°. Soly in water about 55%. LD50 i.v. in rabbits: 163 mg/kg; orally in mice: 600 mg/kg, (Thompson, Warren).
Melting point: mp 254-256°
Toxicity data: LD50 i.v. in rabbits: 163 mg/kg; orally in mice: 600 mg/kg, (Thompson, Warren)
Therap-Cat: Bronchodilator.
Keywords: Bronchodilator; Xanthine Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.

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