Beclamide
Title: Beclamide
CAS Registry Number: 501-68-8
CAS Name: 3-Chloro-N-(phenylmethyl)propanamide
Additional Names: N-benzyl-3-chloropropionamide; N-benzyl-b-chloropropanamide; benzchlorpropamide; chloroethylphenamide
Trademarks: Neuracen (Byk Gulden); Nidrane (Phoenix); Posedrine (Merck KGaA); Seclar (Andromaco)
Molecular Formula: C10H12ClNO
Molecular Weight: 197.66
Percent Composition: C 60.76%, H 6.12%, Cl 17.94%, N 7.09%, O 8.09%
Line Formula: ClCH2CH2CONHCH2C6H5
Literature References: Prepd by the action of b-chloropropionyl chloride on benzylamine in cooled water at pH 8: Cassell, Kushner, US 2569288 (1951 to Am. Cyanamid); Kushner et al., J. Org. Chem. 16, 1283 (1951).
Properties: Large crystals from methanol, mp 94°. Slightly sol in water (0.005 to 0.01%). Moderately sol in the lower alcs. Dec in hot aq acid soln and in hot aq alkaline soln.
Melting point: mp 94°
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant.

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