Bifluranol
Title: Bifluranol
CAS Registry Number: 34633-34-6
CAS Name: rel-4,4¢-[(1R,2S)-1-Ethyl-2-methyl-1,2-ethanediyl]bis[2-fluorophenol]
Additional Names: erythro-3,3¢-difluoro-4,4¢-dihydroxy-a-ethyl--methyldibenzyl
Manufacturers' Codes: BX-341
Trademarks: Prostarex (Biorex)
Molecular Formula: C17H18F2O2
Molecular Weight: 292.32
Percent Composition: C 69.85%, H 6.21%, F 13.00%, O 10.95%
Literature References: Orally active antiprostatic agent. Prepn: J. C. Turner, R. P. Chan, DE 2110428; eidem, US 4051263 (1971, 1977 both to Biorex). Antiprostatic activity: J. B. Dekanski, Br. J. Pharmacol. 71, 11 (1980). Chemistry, disposition in animals: D. J. Pope et al., J. Pharm. Pharmacol. 33, 297 (1981). Metabolism: eidem, ibid. 302.
Properties: Cryst from toluene, mp 158-159°.
Melting point: mp 158-159°
Therap-Cat: Antiandrogen.
Keywords: Antiandrogen.

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