Calcium 3-Aurothio-2-propanol-1-sulfonate
Title: Calcium 3-Aurothio-2-propanol-1-sulfonate
CAS Registry Number: 5743-29-3
CAS Name: [2-(Hydroxy-kO)-3-(mercapto-kS)-1-propanesulfonato(2-)] aurate(1-) calcium (2:1)
Additional Names: [(2-hydroxy-3-sulfopropyl)thio]gold calcium salt; 2-hydroxy-3-mercapto-1-propanesulfonic acid S-gold deriv calcium salt
Trademarks: Chrisanol; Chrysanol; Krizanol
Molecular Formula: C6H12Au2CaO8S4
Molecular Weight: 774.43
Percent Composition: C 9.31%, H 1.56%, Au 50.87%, Ca 5.18%, O 16.53%, S 16.56%
Line Formula: (AuSCH2CHOHCH2SO3)2Ca
Literature References: Prepd by treating sodium thiopropanolsulfonate with gold chloride in the presence of SO2 and converting the sodium salt to the calcium salt by means of calcium chloride: Lipovich, Mones, J. Appl. Chem. (USSR) 18, 20 (1945); cf. GB 265777; Lumière, Perrin, Compt. Rend. 184, 289 (1927).
Properties: Pale yellow powder. Has no definite mp. Soly in water about 2%. Practically insol in organic solvents. Marketed as Oleochrysine which is a suspension plus some Ca gluconate in peach kernel oil.
Therap-Cat: Antiarthritic.
Keywords: Antiarthritic/Antirheumatic.
Status: This monograph has been retired and is no longer subject to revision or update.

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