Title: Carbubarb
CAS Registry Number: 960-05-4
CAS Name: 5-[2-[(Aminocarbonyl)oxy]ethyl]-5-butyl-2,4,6(1H,3H,5H)-pyrimidinetrione
Additional Names: carbamic acid ester with 5-butyl-5-(2-hydroxyethyl)barbituric acid; 5-butyl-5-carbamoyloxyethylbarbituric acid; 5-butyl-5-(2-hydroxyethyl)barbituric acid carbamate; carbamic acid ester with 5-(b-hydroxyethyl)-5-butylmalonylurea; 5-(b-hydroxyethyl)-5-butylmalonylurea carbamate
Trademarks: Nogexan (Farmex)
Molecular Formula: C11H17N3O5
Molecular Weight: 271.27
Percent Composition: C 48.70%, H 6.32%, N 15.49%, O 29.49%
Literature References: Prepn: FR M1059 (1962 to Consortium Mondial des Grandes Marques), C.A. 59, 7539c (1963); Buzas, US 3150137 (1964). Purification and toxicity: FR M2633 (1964 to Interco Fribourg), C.A. 62, 1671e (1965).
Properties: Crystals from ethanol, mp 192-194°. LD50 s.c. in mice: 1.4 g/kg (FR M2633).
Melting point: mp 192-194°
Toxicity data: LD50 s.c. in mice: 1.4 g/kg (FR M2633)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.

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