Title: Chlorthion® (Bayer)
CAS Registry Number: 500-28-7
CAS Name: Phosphorothioic acid O-(3-chloro-4-nitrophenyl) O,O-dimethyl ester
Additional Names: O,O-dimethyl O-(3-chloro-4-nitrophenyl) thionophosphate; p-nitro-m-chlorophenyl dimethyl thionophosphate
Manufacturers' Codes: compd 22/190
Trademarks: Chlorothion
Molecular Formula: C8H9ClNO5PS
Molecular Weight: 297.65
Percent Composition: C 32.28%, H 3.05%, Cl 11.91%, N 4.71%, O 26.88%, P 10.41%, S 10.77%
Literature References: Prepn: Schrader, Angew. Chem. 66, 265 (1954); US 2701259 (1955 to Bayer). Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969).
Properties: The pure compound as yellow crystals, mp 21°. d420 1.437. nD20 1.5661. Commercial product is a yellow oil, bp0.1 125°. Miscible in benzene, alcohol, ether. Practically insol in water. Hydrolyzed by alkali. LD50 in male, female rats (mg/kg): 880, 980 orally (Gaines).
Melting point: mp 21°
Boiling point: bp0.1 125°
Index of refraction: nD20 1.5661
Density: d420 1.437
Toxicity data: LD50 in male, female rats (mg/kg): 880, 980 orally (Gaines)
CAUTION: Cholinesterase inhibitor. Symptoms similar to parathion.
Use: Insecticide.
Status: This monograph has been retired and is no longer subject to revision or update.

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