Etofylline Nicotinate
Title: Etofylline Nicotinate
CAS Registry Number: 13425-39-3
CAS Name: 3-Pyridinecarboxylic acid 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl ester
Additional Names: nicotinic acid ester with 7-(2-hydroxyethyl)theophylline; 7-(2-hydroxyethyl)theophylline nicotinate
Trademarks: Hesotanol; Hesotin
Molecular Formula: C15H15N5O4
Molecular Weight: 329.31
Percent Composition: C 54.71%, H 4.59%, N 21.27%, O 19.43%
Literature References: Prepn: Pongratz, Zirm, Monatsh. Chem. 88, 330 (1957). Pharmacology: Fischbach, Haas, Arzneim.-Forsch. 17, 313 (1967).
Properties: Fine dendritic needles from abs alcohol, mp 151-152°. Hydrated crystals from water. One gram dissolves in 50 ml boiling water; moderately sol in alcohol.
Melting point: mp 151-152°
Therap-Cat: Vasodilator.

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