Ferrous Gluconate
Title: Ferrous Gluconate
CAS Registry Number: 299-29-6
CAS Name: Bis(D-gluconato-O1,O2)-iron
Trademarks: Fergon (Miles); Ferlucon; Ferronicum (Sandoz); Iromon (Gador); Irox; Nionate (Nion)
Molecular Formula: C12H22FeO14
Molecular Weight: 446.14
Percent Composition: C 32.31%, H 4.97%, Fe 12.52%, O 50.21%
Line Formula: Fe[HOCH2(CHOH)4CO2]2
Literature References: Prepd from Ba gluconate and FeSO4. Prepn of isotonic solns: Hammarlund, Pharm. Acta Helv. 35, 593 (1960). Toxicity study: Hoppe et al., Am. J. Med. Sci. 230, 491 (1955).
Derivative Type: Dihydrate
Properties: Yellowish-gray or pale greenish-yellow powder. Slight odor of caramel. Acid to litmus. Sol in water. Practically insol in alcohol. Aq solns are stabilized by the addition of glucose. Extensive stability studies on aq solns: Johnson, Thomas, J. Pharm. Pharmacol. 6, 1037 (1954). LD50 in mice: 114 mg/kg i.v.; 3.7 g/kg orally (Hoppe).
Toxicity data: LD50 in mice: 114 mg/kg i.v.; 3.7 g/kg orally (Hoppe)
Use: As coloring and flavoring in foods.
Therap-Cat: Hematinic.
Keywords: Hematinic.

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