Title: Isoflurane
CAS Registry Number: 26675-46-7
CAS Name: 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
Additional Names: 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether
Manufacturers' Codes: compd 469
Trademarks: Aerrane (Baxter); Forane (Ohmeda); Forene (Abbott)
Molecular Formula: C3H2ClF5O
Molecular Weight: 184.49
Percent Composition: C 19.53%, H 1.09%, Cl 19.22%, F 51.49%, O 8.67%
Line Formula: CF3CHClOCHF2
Literature References: Prepn: Croix, Terrell, DE 1814962 (1969); Terrell, US 3535388; US 3535425 (both 1970 to Air Reduction); Terrell et al., J. Med. Chem. 14, 517 (1971). Series of articles on pharmacology: Anesthesiology 35, 8-53 (1971); Byles et al., Can. Anaesth. Soc. J. 18, 376-407 (1971). Enantiomeric resolution: J. Meinwald et al., Science 251, 560 (1991).
Properties: Clear, colorless liquid having a slight odor. bp 48.5°. Vapor pressure at 25°: 330 mm. sp gr 1.45. nD20 1.3002. Nonflammable; soda lime stable. Easily miscible with organic liquids including fats and oils.
Boiling point: bp 48.5°
Index of refraction: nD20 1.3002
Use: Solvent and dispersant for fluorinated materials.
Therap-Cat: Anesthetic (inhalation).
Therap-Cat-Vet: Anesthetic (inhalation).
Keywords: Anesthetic (Inhalation).

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