Ketobemidone
Title: Ketobemidone
CAS Registry Number: 469-79-4
CAS Name: 1-[4-(3-Hydroxyphenyl)-1-methyl-4-piperidyl]-1-propanone
Additional Names: 4-(m-hydroxyphenyl)-1-methyl-4-piperidyl ethyl ketone
Molecular Formula: C15H21NO2
Molecular Weight: 247.33
Percent Composition: C 72.84%, H 8.56%, N 5.66%, O 12.94%
Literature References: Prepn: Suter, Abstracts of First National Medicinal Chemistry Symposium of the A.C.S. (Ann Arbor, 1948) p 20; GB 591992 and GB 609763 (1947 and 1948 to Ciba); Eisleb, US 2167351; US 2242575 and US 2248018 (1939 and 1941 to Winthrop); DE 752755 (1952 to I. G. Farben). Metabolism in man: U. Bondesson et al., Drug Metab. Dispos. 9, 376 (1981).
Properties: Crystals, mp 156-157°.
Melting point: mp 156-157°
 
Derivative Type: Hydrochloride
CAS Registry Number: 5965-49-1
Manufacturers' Codes: Hoechst 10720; Win-1539
Trademarks: Cliradon (Novartis); Cymidon; Ketogan (Lundbeck); Ketogin (Lundbeck)
Molecular Formula: C15H21NO2.HCl
Molecular Weight: 283.79
Percent Composition: C 63.48%, H 7.81%, N 4.94%, O 11.28%, Cl 12.49%
Properties: Crystals, mp 201-202°. Sol in water; slightly sol in alcohol. Aq solns may be sterilized by boiling for short periods.
Melting point: mp 201-202°
 
NOTE: This is a controlled substance (opiate): 21 CFR, 1308.11.
Therap-Cat: Analgesic (narcotic).
Keywords: Analgesic (Narcotic).

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