Nicarbazin
Title: Nicarbazin
CAS Registry Number: 330-95-0
CAS Name: N,N¢-Bis(4-nitrophenyl)urea, compd with 4,6-dimethyl-2(1H)-pyrimidinone (1:1)
Additional Names: 4,4¢-dinitrocarbanilide compd with 4,6-dimethyl-2-pyrimidinol (1:1)
Trademarks: Nicarb (Merck & Co.); Nicoxin; Nicrazin (Merck & Co.)
Molecular Formula: C19H18N6O6
Molecular Weight: 426.38
Percent Composition: C 53.52%, H 4.26%, N 19.71%, O 22.51%
Literature References: Prepn: Cuckler et al., Science 122, 244 (1955); Basso, O'Neill, US 2731382; US 2731383; US 2731384 (all 1956 to Merck & Co.). Effect on nutritional encephalopathy in chicks: I. Bartov, P. Budowski, Poult. Sci. 58, 597 (1979).
Properties: Crystals, dec 265-275°. uv max (concd H2SO4): 298 nm (A1%1cm 670). Practically insol in water. Complex is slowly dec by trituration with water, or more rapidly by dil aq acids. The dry crystals are strongly electrostatic and present some dry-mixing problems.
Absorption maximum: uv max (concd H2SO4): 298 nm (A1%1cm 670)
Therap-Cat-Vet: Coccidiostat.

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