Phenglutarimide
Title: Phenglutarimide
CAS Registry Number: 1156-05-4
CAS Name: 3-[2-(Diethylamino)ethyl]-3-phenyl-2,6-piperidinedione
Additional Names: 2-(2-diethylaminoethyl)-2-phenylglutarimide; a-phenyl-a-(diethylaminoethyl)glutarimide; 3-phenyl-3-(b-diethylaminoethyl)-2,6-dioxopiperidine
Molecular Formula: C17H24N2O2
Molecular Weight: 288.38
Percent Composition: C 70.80%, H 8.39%, N 9.71%, O 11.10%
Literature References: Anticholinergic. Prepn: Tagmann et al., Helv. Chim. Acta 35, 1235 (1952); 37, 185 (1954); Hoffmann, Tagmann, US 2664424 (1953 to Ciba).
Properties: Crystals from isopropanol, mp 125-127°. Can also be crystallized from a mixture of ethyl acetate and ligroin.
Melting point: mp 125-127°
 
Derivative Type: Hydrochloride
CAS Registry Number: 1674-96-0
Trademarks: Aturbane (Novartis); Aturbal
Molecular Formula: C17H24N2O2.HCl
Molecular Weight: 324.85
Percent Composition: C 62.85%, H 7.76%, N 8.62%, O 9.85%, Cl 10.91%
Properties: Crystals from methanol + ethyl acetate, dec 168-172°, also 176-177°. Freely sol in water. Dec by alkali.
 
Therap-Cat: Antiparkinsonian.
Keywords: Antiparkinsonian; Antimuscarinic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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