Sodium Citrate
Title: Sodium Citrate
CAS Registry Number: 68-04-2
CAS Name: 2-Hydroxy-1,2,3-propanetricarboxylic acid trisodium salt
Additional Names: trisodium citrate
Trademarks: Citrosodine (GSK); Cystemme (Abbott); Urisal (Sanofi-Synthelabo)
Molecular Formula: C6H5Na3O7
Molecular Weight: 258.07
Percent Composition: C 27.92%, H 1.95%, Na 26.73%, O 43.40%
Literature References: Anticoagulant use in blood transfusion: R. Weil, J. Am. Med. Assoc. 64, 425 (1915); cf. ibid. 250, 1901 (1983). Toxicity study: C. M. Gruber, Jr., W. A. Halbeisen, J. Pharmacol. Exp. Ther. 94, 65 (1948). Clinical evaluation of antacid efficacy: C. P. Gibbs et al., Anesthesiology 57, 44 (1982); of effects on athletic performance: V. Oöpik et al., Br. J. Sports Med. 37, 485 (2003).
Properties: LD50 in rats, mice (mmol/kg): 6.0, 5.5 i.p. (Gruber, Halbeisen).
Toxicity data: LD50 in rats, mice (mmol/kg): 6.0, 5.5 i.p. (Gruber, Halbeisen)
Derivative Type: Dihydrate
CAS Registry Number: 6132-04-3
Properties: White, odorless crystals, granules or powder; cool, saline taste. Stable in air; becomes anhydrous at 150°. Sol in 1.3 parts water, 0.6 part boiling water. Insol in alcohol. The aq soln is slightly alkaline to litmus. pH about 8.
Use: Anticoagulant for collection of blood. In photography; as sequestering agent to remove trace metals; as emulsifier, acidulant and sequestrant in foods.
Therap-Cat: Systemic alkalinizing agent.
Keywords: Alkalinizing Agent.

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