Strychnine N6-Oxide
Title: Strychnine N6-Oxide
CAS Registry Number: 7248-28-4
CAS Name: Strychnidin-10-one 19-oxide
Trademarks: Genostrychnine
Molecular Formula: C21H22N2O3
Molecular Weight: 350.41
Percent Composition: C 71.98%, H 6.33%, N 7.99%, O 13.70%
Literature References: Prepn: Pictet, Mattison, Ber. 38, 2782 (1905); Bailey, Robinson, J. Chem. Soc. 1948, 703; Zellner, US 2758113 (1956 to Donau-Pharmazie).
Properties: Monoclinic prisms from water, dec 207°. pK 5.17. Freely sol in alc, glacial acetic acid, chloroform; fairly sol in water; sparingly sol in benzene. Practically insol in ether, petr ether.
pKa: pK 5.17
Derivative Type: Hydriodide
Properties: Light yellow plates from hot water, dec 253°.
Derivative Type: Nitrate
Properties: Small transparent prisms from water, dec 250°.

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