Title: Thioacetamide
CAS Registry Number: 62-55-5
CAS Name: Ethanethioamide
Molecular Formula: C2H5NS
Molecular Weight: 75.13
Percent Composition: C 31.97%, H 6.71%, N 18.64%, S 42.68%
Line Formula: CH3CSNH2
Literature References: Prepd by heating ammonium acetate and aluminum sulfide: Kindler, Finndorf, Ber. 54, 1080 (1921); from acetonitrile + H2S: Kindler, Ann. 431, 203 (1923); from acetamide + K3PS4: Schultz, Ranke, Arch. Pharm. 294, 82 (1961). Toxicity data: Ambrose et al., J. Ind. Hyg. Toxicol. 31, 158 (1949). Review of uses: H. F. Walton, Thioacetamide as Analytical Reagent, Arapahoe Chemicals, Inc., Boulder, Colorado.
Properties: Crystals from benzene, mp 113-114°. Slight odor of mercaptans. uv max (water): 210, 261, 318 nm (log e 3.66, 4.08, 1.8). Soly in water at 25° 16.3 g/100 ml; in ethanol 26.4 g/100 g. Sparingly sol in ether. MLD orally in rats: 200 mg/kg (Ambrose).
Melting point: mp 113-114°
Absorption maximum: uv max (water): 210, 261, 318 nm (log e 3.66, 4.08, 1.8)
Toxicity data: MLD orally in rats: 200 mg/kg (Ambrose)
CAUTION: This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-247.
Use: Substitute for H2S in laboratory qualitative analyses.

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