Adrenalone
Title: Adrenalone
CAS Registry Number: 99-45-6
CAS Name: 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone
Additional Names: 3¢,4¢-dihydroxy-2-(methylamino)acetophenone; 3,4-dihydroxy-a-methylaminoacetophenone; adrenone; 4-methylaminocetopyrocatechol
Trademarks: Stryphnon (Salus-Braumapharm)
Molecular Formula: C9H11NO3
Molecular Weight: 181.19
Percent Composition: C 59.66%, H 6.12%, N 7.73%, O 26.49%
Literature References: Intermediate in some epinephrine manuf processes. Prepd from 4-chloroacetylpyrocatechol and methylamine: DE 152814 (Hoechst); Stolz, Ber. 37, 4152 (1904); by heating a-(p-toluene sulfonylmethylamino)-3,4-dimethoxyacetophenone with HCl under pressure: DE 277540 (Bayer); Frdl. 12, 764; Chem. Zentralbl. 1914, II, 740.
Properties: Needles, dec 235-236°. Sparingly sol in water, alc, ether.
 
Derivative Type: Hydrochloride
CAS Registry Number: 62-13-5
Trademarks: Stryphnasal (Sertõner)
Molecular Formula: C9H11NO3.HCl
Molecular Weight: 217.65
Percent Composition: C 49.67%, H 5.56%, N 6.44%, O 22.05%, Cl 16.29%
Properties: Crystals, mp 243°. Freely sol in water; sol in alcohol. Insol in ether. Aq solns are neutral to litmus.
Melting point: mp 243°
 
Therap-Cat: Hemostatic.
Keywords: a-Adrenergic Agonist; Hemostatic.

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