Ambazone
Title: Ambazone
CAS Registry Number: 539-21-9
CAS Name: 2-[4-[(Aminoiminomethyl)hydrazono]-2,5-cyclohexadien-1-ylidene]hydrazinecarbothioamide
Additional Names: [(4-oxo-2,5-cyclohexadien-1-ylidene)amino]guanidine thiosemicarbazone; 1-amidinohydrazono-4-thiosemicarbazono-2,5-cyclohexadiene; p-benzoquinone amidinohydrazone thiosemicarbazone; benzoquinone guanylhydrazone thiosemicarbazone
Trademarks: Iversal (Bayer); Primal (Bayer)
Molecular Formula: C8H11N7S
Molecular Weight: 237.28
Percent Composition: C 40.49%, H 4.67%, N 41.32%, S 13.51%
Literature References: Prepn from p-benzoquinone and aminoguanidine followed by treatment of the reaction product with thiosemicarbazide in acid soln: Petersen, Domagk, Naturwissenschaften 41, 10 (1954); eidem, DE 965723 and GB 774794 (both 1957 to Bayer).
 
Derivative Type: Monohydrate
Properties: Brown or copper-colored crystals from water, dec 195°. Sparingly soluble in water. Moderately sol in alcohol, acetone. Freely sol in DMF, dilute acids.
 
Therap-Cat: Antibacterial.
Keywords: Antiseptic/Disinfectant; Guanidines.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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