Amprolium
Title: Amprolium
CAS Registry Number: 121-25-5
CAS Name: 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride
Additional Names: 1-[(4-amino-2-propyl-5-pyrimidinyl)methyl]-2-picolinium chloride
Trademarks: Corid (Merck & Co.)
Molecular Formula: C14H19ClN4
Molecular Weight: 278.78
Percent Composition: C 60.32%, H 6.87%, Cl 12.72%, N 20.10%
Literature References: Prepn: Rogers et al., J. Am. Chem. Soc. 82, 2974 (1960); Rogers, Sarett, US 3020277 (1962 to Merck & Co.), see also US 3020200. Formulations as poultry feed: Rogers, Sarett, US 3065132 (1962 to Merck & Co.).
 
Derivative Type: Hydrochloride
Trademarks: Amprol (Merck & Co.)
Molecular Formula: C14H19ClN4.HCl
Molecular Weight: 315.24
Percent Composition: C 53.34%, H 6.39%, Cl 22.49%, N 17.77%
Properties: Crystals from methanol + ethanol, dec 248-249°. Freely sol in water, methanol, 95% ethanol, dimethylformamide. Sparingly sol in abs ethanol. Practically insol in isopropanol, butanol, dioxane, acetone, ethyl acetate, acetonitrile, isooctane. pH of 10% aq soln 2.5-3.0.
 
Therap-Cat-Vet: Coccidiostat.

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