Title: Broxyquinoline
CAS Registry Number: 521-74-4
CAS Name: 5,7-Dibromo-8-quinolinol
Additional Names: 5,7-dibromo-8-hydroxyquinoline
Trademarks: Brodiar (Intervet); Broxykinolin; Colepur (Draco); Fenilor (UCB); Intensopan (Sandoz)
Molecular Formula: C9H5Br2NO
Molecular Weight: 302.95
Percent Composition: C 35.68%, H 1.66%, Br 52.75%, N 4.62%, O 5.28%
Literature References: Prepn by bromination of 5-formyl-8-quinolinol: Matsumura, Ito, J. Am. Chem. Soc. 77, 6671 (1955); by bromination of 8-hydroxyquinaldine: Irving, Pinnington, J. Chem. Soc. 1957, 285; by bromination of 8-quinolinol: Luis, Palomo, Afinidad 28, 163 (1951), C.A. 47, 10533d (1953); Zinnei, Fiedler, Arch. Pharm. 291, 493 (1958); Aristov, Kostina, Zh. Obshch. Khim. 34, 3421 (1964). Crystal structure: Kashino, Haisa, Bull. Chem. Soc. Jpn. 46, 1094 (1973). Metabolism: Rodriguez, Close, Biochem. Pharmacol. 17, 1647 (1968).
Properties: Monoclinic needles from alc. d 2.189. mp 196°. Freely sol in chloroform, alcohol, benzene, acetic acid; slightly sol in ether. Practically insol in water.
Melting point: mp 196°
Density: d 2.189
Use: In testing for Cu, Fe, Ti.
Therap-Cat: Antiseptic; disinfectant.
Keywords: Antiseptic/Disinfectant; Quinolines.

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