Chloropyramine
Title: Chloropyramine
CAS Registry Number: 59-32-5
CAS Name: N-[(4-Chlorophenyl)methyl]-N¢,N¢-dimethyl-N-2-pyridinyl-1,2-ethanediamine
Additional Names: 2-[(p-chlorobenzyl)[2-(dimethylamino)ethyl]amino]pyridine; N-dimethylaminoethyl-N-p-chlorobenzyl-a-aminopyridine; N,N-dimethyl-N¢-(p-chlorobenzyl)-N¢-(2-pyridyl)ethylenediamine; halopyramine
Molecular Formula: C16H20ClN3
Molecular Weight: 289.80
Percent Composition: C 66.31%, H 6.96%, Cl 12.23%, N 14.50%
Literature References: Prepn: Phillips, Cates, US 2607778 (1952 to Merck & Co.); Howard, US 2569314 (1951 to Am. Cyanamid); CH 264754; CH 266234; CH 266235 (1950); GB 651596 (1951) (all to Geigy).
Properties: Light yellow, viscous, oily liquid. Pungent odor. bp0.2 154-155°.
Boiling point: bp0.2 154-155°
 
Derivative Type: Hydrochloride
CAS Registry Number: 6170-42-9
Trademarks: Synopen (Novartis); Synpen (Novartis)
Molecular Formula: C16H20ClN3.HCl
Molecular Weight: 326.26
Percent Composition: C 58.90%, H 6.49%, Cl 21.73%, N 12.88%
Properties: Crystals from acetone, mp 172-174°.
Melting point: mp 172-174°
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Ethylenediamine Derivatives.

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