Clortermine
Title: Clortermine
CAS Registry Number: 10389-73-8
CAS Name: 2-Chloro-a,a-dimethylbenzeneethanamine
Additional Names: o-chloro-a,a-dimethylphenethylamine; 1-(o-chlorophenyl)-2-methyl-2-propylamine; 1-(o-chlorophenyl)-2-methyl-2-aminopropane
Molecular Formula: C10H14ClN
Molecular Weight: 183.68
Percent Composition: C 65.39%, H 7.68%, Cl 19.30%, N 7.63%
Literature References: Prepn and use as anorexic agent: BE 665244; GB 1066616; Finocchio, Huebner, US 3415937 (1965, 1967, 1968, all to Ciba). Toxicity data: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: bp16 116-118°.
Boiling point: bp16 116-118°
 
Derivative Type: Hydrochloride
CAS Registry Number: 10389-72-7
Manufacturers' Codes: Su-10568
Trademarks: Voranil (USV)
Molecular Formula: C10H14ClN.HCl
Molecular Weight: 220.14
Percent Composition: C 54.56%, H 6.87%, Cl 32.21%, N 6.36%
Properties: Crystals from ethanol, mp 245-246°. LD50 orally in rats: 332 ±23 mg/kg (Goldenthal).
Melting point: mp 245-246°
Toxicity data: LD50 orally in rats: 332 ±23 mg/kg (Goldenthal)
 
NOTE: This is a controlled substance (stimulant): 21 CFR, 1308.13.
Therap-Cat: Anorexic.
Keywords: Anorexic; CNS Stimulant.

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