Cyclorphan
Title: Cyclorphan
CAS Registry Number: 4163-15-9
CAS Name: 17-(Cyclopropylmethyl)morphinan-3-ol
Additional Names: (-)-3-hydroxy-N-cyclopropylmethylmorphinan
Molecular Formula: C20H27NO
Molecular Weight: 297.43
Percent Composition: C 80.76%, H 9.15%, N 4.71%, O 5.38%
Literature References: Prepn: Gates, Montzka, J. Med. Chem. 7, 127 (1964); Gates, US 3285922 (1966 to Res. Corp.). Pharmacology: Harris et al., Arch. Int. Pharmacodyn. Ther. 165, 112 (1967).
Properties: Crystals from ethyl acetate, mp 187.5-189°. [a]D30 -120° (c = 2.26). LD50 in mice, rats (mg/kg): 24, 23 i.v. (Gates, 1966).
Melting point: mp 187.5-189°
Optical Rotation: [a]D30 -120° (c = 2.26)
Toxicity data: LD50 in mice, rats (mg/kg): 24, 23 i.v. (Gates, 1966)

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