Demexiptiline
Title: Demexiptiline
CAS Registry Number: 24701-51-7
CAS Name: 5H-Dibenzo[a,d]cyclohepten-5-one O-[2-(methylamino)ethyl]oxime
Molecular Formula: C18H18N2O
Molecular Weight: 278.35
Percent Composition: C 77.67%, H 6.52%, N 10.06%, O 5.75%
Literature References: Prepn: S. Schütz et al., DE 1247302; eidem, US 3963778 (1967, 1976 both to Bayer). Synthesis and pharmacological properties: G. Aichinger et al., Arzneim.-Forsch. 19, 838 (1969); S. Rossi et al., Farmaco Ed. Sci. 24, 685 (1969).
Properties: Colorless oil.
 
Derivative Type: Hydrochloride
CAS Registry Number: 18059-99-9
Manufacturers' Codes: LM-2909
Trademarks: Deparon (Aron)
Molecular Formula: C18H18N2O.HCl
Molecular Weight: 314.81
Percent Composition: C 68.67%, H 6.08%, N 8.90%, O 5.08%, Cl 11.26%
Properties: Crystals from isopropanol, mp 232-233°. LD50 in rats (mg/kg): 330 orally, 25 i.v. (Rossi).
Melting point: mp 232-233°
Toxicity data: LD50 in rats (mg/kg): 330 orally, 25 i.v. (Rossi)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics.

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