Dichlorphenamide
Title: Dichlorphenamide
CAS Registry Number: 120-97-8
CAS Name: 4,5-Dichloro-1,3-benzenedisulfonamide
Additional Names: 1,3-disulfamyl-4,5-dichlorobenzene; 4,5-dichloro-1,3-disulfamoylbenzene
Trademarks: Antidrasi; Daranide (Merck & Co.); Oratrol (Alcon)
Molecular Formula: C6H6Cl2N2O4S2
Molecular Weight: 305.16
Percent Composition: C 23.62%, H 1.98%, Cl 23.24%, N 9.18%, O 20.97%, S 21.02%
Literature References: Prepn: Schultz, US 2835702 (1958 to Merck & Co.).
Properties: Needles from DMSO + water, mp 239-241° (patent, mp 228.5-229°). Practically insol in water. Sol in alkaline solns.
Melting point: mp 239-241° (patent, mp 228.5-229°)
Therap-Cat: Carbonic anhydrase inhibitor.
Keywords: Antiglaucoma; Carbonic Anhydrase Inhibitor.

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