Dimetacrine
Title: Dimetacrine
CAS Registry Number: 4757-55-5
CAS Name: N,N,9,9-Tetramethyl-10(9H)-acridinepropanamine
Additional Names: 10-[3-(dimethylamino)propyl]-9,9-dimethylacridan; 5,5-dimethyl-10-dimethylaminopropylacridan; dimethacrine
Molecular Formula: C20H26N2
Molecular Weight: 294.43
Percent Composition: C 81.59%, H 8.90%, N 9.51%
Literature References: Prepn: Holm, GB 933875 (1963 to Kefalas), C.A. 60, 510a (1964); Molnar, Wagner-Jauregg, Helv. Chim. Acta 48, 1782 (1965); FR 1438357 (1966 to Siegfried), C.A. 66, 10856k (1967). Pharmacology and metabolism: Schatz et al., Arzneim.-Forsch. 18, 862 (1968); Ishitani et al., Jpn. J. Pharmacol. 20, 432 (1970).
Properties: Free base, bp1 200°.
Boiling point: bp1 200°
 
Derivative Type: Hydrochloride
Molecular Formula: C20H26N2.HCl
Molecular Weight: 330.89
Percent Composition: C 72.60%, H 8.22%, N 8.47%, Cl 10.71%
Properties: Crystals from abs alc + acetone, mp 151-154°.
Melting point: mp 151-154°
 
Derivative Type: Tartrate
CAS Registry Number: 3759-07-7
Manufacturers' Codes: SD-709
Trademarks: Istonil (Siegfried)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics.

Others monographs:
EverolimusFusaric AcidCobaltic AcetateGlucose Oxidase
Interleukin-1 Receptor AntagonistPhenserineDiethylsilaneHexafluorobenzene
Phosphorus OxybromideDigitogenin2,3:6,7-DibenzphenanthreneVinylidene Chloride
JosamycinLoprazolamHNEn-Butylamine
©2016 DrugLead US FDA&EMEA