Doxacurium Chloride
Title: Doxacurium Chloride
CAS Registry Number: 106819-53-8
CAS Name: (1R,1¢S,2S,2¢R)-rel-2,2¢-[(1,4-Dioxo-1,4-butanediyl)bis(oxy-3,1-propanediyl)]bis[1,2,3,4-tetrahydro-6,7,8-trimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]isoquinolinium] dichloride
Additional Names: (1R,2S;1S,2R)-1,2,3,4-tetrahydro-2-(3-hydroxypropyl)-6,7,8-trimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)isoquinolinium chloride succinate (2:1); trans,trans-2,2¢-[dimethylenebis(carbonyloxytrimethylene)]bis[1,2,3,4-tetrahydro-6,7,8-trimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)isoquinolinium] dichloride
Manufacturers' Codes: BW-A938U
Trademarks: Nuromax (Glaxo Wellcome)
Molecular Formula: C56H78Cl2N2O16
Molecular Weight: 1106.13
Percent Composition: C 60.81%, H 7.11%, Cl 6.41%, N 2.53%, O 23.14%
Literature References: Benzylisoquinolinium, competitive neuromuscular blocker. Prepn: H. A. El-Sayad et al., EP 54309 (1982 to Wellcome Found.); eidem, US 4701460 (1987 to Burroughs Wellcome). Clinical pharmacology: S. J. Basta et al., Anesthesiology 69, 478 (1988). Clinical evaluation during anesthesia: R. P. F. Scott, J. Norman, Br. J. Anaesth. 62, 373 (1989).
Properties: Amorphous solid. Sol in water.
Therap-Cat: Neuromuscular blocking agent.
Keywords: Neuromuscular Blocking Agent; Nondepolarizing Agents.

Others monographs:
Sevoflurane1,2-NaphthoquinoneBromthymol BlueRyania
1-CyanoimidazoleEthopabateThallium Chloride2,2'-Dithiobis[benzothiazole]
Bismuth Potassium IodideDaunorubicinCholine Dihydrogen CitratePyrethrosin
Stannic BromideNeurineAzacitidineAzosemide
©2016 DrugLead US FDA&EMEA