Epoxiconazole
Title: Epoxiconazole
CAS Registry Number: 133855-98-8; 106325-08-0 (undefined)
CAS Name: rel-1-[[(2R,3S)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole
Additional Names: (2RS,3RS)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)-propyl]-1H-1,2,4-triazole
Manufacturers' Codes: BAS-480-F
Trademarks: Opus (BASF)
Molecular Formula: C17H13ClFN3O
Molecular Weight: 329.76
Percent Composition: C 61.92%, H 3.97%, Cl 10.75%, F 5.76%, N 12.74%, O 4.85%
Literature References: Ergosterol biosynthesis inhibitor. Prepn: S. Karbach et al., EP 196038; eidem, US 4906652 (1986, 1990 both to BASF). Properties and field trials: E. Ammermann et al., Brighton Crop Prot. Conf. - Pests Dis. 1990, 407; R. Saur et al., ibid. 831. Mode of action: A. Akers et al., ibid. 837. Use in combination with fenpropimorph, q.v.: R. Saur et al., Gesunde Pflanz. 46, 61 (1994). Brief review: A. Floquet, N. Martin, Phytoma 449, 54-57 (1993).
Properties: Crystals from diisopropyl ether, mp 136.2°. Soly at 20° (g/100 ml): water 6.63 ´ 10-4, acetone 18, dichloromethane 14, n-heptane <0.1. Partition coefficient (n-octanol/ water at pH 7) 3.44. LD50 in rats (mg/kg): >5000 orally, >2000 dermally; LC50 in rats (4 hr): >5.3 mg/l (dust aerosol) (Ammermann).
Melting point: mp 136.2°
Log P: Partition coefficient (n-octanol/ water at pH 7) 3.44
Toxicity data: LD50 in rats (mg/kg): >5000 orally, >2000 dermally; LC50 in rats (4 hr): >5.3 mg/l (dust aerosol) (Ammermann)
Use: Agricultural fungicide.

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