Ethyl Acetate
Title: Ethyl Acetate
CAS Registry Number: 141-78-6
CAS Name: Acetic acid ethyl ester
Additional Names: acetic ether; vinegar naphtha
Molecular Formula: C4H8O2
Molecular Weight: 88.11
Percent Composition: C 54.53%, H 9.15%, O 36.32%
Line Formula: CH3COOC2H5
Literature References: Obtained by the slow distillation of a mixture of acetic acid, ethyl alc, and sulfuric acid: Alheritiere, Mercier, US 2787636 (1957 to Usines de Melle); Faith, Keyes & Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 350-354. Toxicity: H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 23, 95 (1962).
Properties: Clear, volatile, flammable liq; characteristic fruity odor; pleasant taste when diluted. Slowly dec by moisture, then acquires an acid reaction. Absorbs water (up to 3.3% w/w). d420 0.902; d2525 0.898. bp 77°. mp -83°. Ignition temp 800°F. Explosive limits (% vol in air): 2.2 to 11.5. nD20 1.3719. Vapor density 3.04 (air = 1). One ml dissolves in 10 ml water at 25°; more sol at lower and less sol at higher temps. Misc with alc, acetone, chloroform, ether. Azeotropic mixture with water (6.1% w/w) bp 70.4°. Azeotropic mixture with water (7.8% w/w) and alc (9.0% w/w) bp 70.3°. Keep tightly closed in a cool place and away from fire. LD50 orally in rats: 11.3 ml/kg (Smyth).
Melting point: mp -83°
Boiling point: bp 77°; bp 70.4°; bp 70.3°
Index of refraction: nD20 1.3719
Density: d420 0.902; d2525 0.898
Toxicity data: LD50 orally in rats: 11.3 ml/kg (Smyth)
CAUTION: Potential symptoms of overexposure are irritation of eyes, skin, nose and throat; narcosis; dermatitis. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 130.
Use: Pharmaceutic aid (flavor); artificial fruit essences; solvent for nitrocellulose, varnishes, lacquers, and aeroplane dopes; manuf smokeless powder, artificial leather, photographic films and plates, artificial silk, perfumes; cleaning textiles, etc.

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