Furazabol
Title: Furazabol
CAS Registry Number: 1239-29-8
CAS Name: (5a,17b)-17-Methylandrostano[2,3-c][1,2,5]oxadiazol-17-ol
Additional Names: 17b-hydroxy-17a-methyl-5a-androstano[2,3-c]furazan; androfurazanol; furazalon
Manufacturers' Codes: DH-245
Trademarks: Miotolon (Daiichi)
Molecular Formula: C20H30N2O2
Molecular Weight: 330.46
Percent Composition: C 72.69%, H 9.15%, N 8.48%, O 9.68%
Literature References: Anabolic steroid with hypocholesterolemic properties. Prepn: G. Ohta et al., BE 645743; eidem, US 3245988 (1964, 1966 both to Daiichi Seiyaku); Shimizu et al., Chem. Pharm. Bull. 13, 895 (1965); Ohta et al., ibid. 1445. Pharmacological studies: Kasahara et al., ibid. 13, 1460 (1965); 16, 1456, 1460 (1968). Toxicity: eidem, ibid. 14, 285 (1966). Metabolic studies: Takegoshi et al., ibid. 20, 1243 (1972). GC-MS determn in urine: T. Kim et al., J. Chromatogr. B 687, 79 (1996).
Properties: Needles from methanol, mp 152-153°. [a]D +39.4° (c = 1.42 in CHCl3). uv max (ethanol): 217 nm (e 4300). LD50 in mice (g/kg): 2.330 orally; >4 s.c.; 0.494 i.p. (Kasahara, 1966).
Melting point: mp 152-153°
Optical Rotation: [a]D +39.4° (c = 1.42 in CHCl3)
Absorption maximum: uv max (ethanol): 217 nm (e 4300)
Toxicity data: LD50 in mice (g/kg): 2.330 orally; >4 s.c.; 0.494 i.p. (Kasahara, 1966)
NOTE: This is a controlled substance (anabolic steroid): 21 CFR, 1308.13, as defined in 1300.01.

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