Gestonorone Caproate
Title: Gestonorone Caproate
CAS Registry Number: 1253-28-7
CAS Name: 17-[(1-Oxohexyl)oxy]-19-norpregn-4-ene-3,20-dione
Additional Names: 17-hydroxy-19-norpregn-4-ene-3,20-dione hexanoate; 17a-hydroxy-19-norprogesterone caproate; 17b-acetyl-17-hydroxyestr-4-ene-3-one hexanoate; gestronol caproate
Manufacturers' Codes: SH-582
Trademarks: Depostat (Schering AG)
Molecular Formula: C26H38O4
Molecular Weight: 414.58
Percent Composition: C 75.32%, H 9.24%, O 15.44%
Literature References: Prepn: Popper et al., Arzneim.-Forsch. 19, 352 (1969); Popper et al., DE 1074582 (1960 to Schering). Pharmacological studies: Junkmann, Anglo-Ger. Med. Rev. 1, 385 (1962). Metabolism: Breuer, Lisboa, Acta Endocrinol. 51, 114 (1966).
Properties: Crystals, mp 123-124°. [a]D +13° (chloroform). uv max: 239 nm (e 17540).
Melting point: mp 123-124°
Optical Rotation: [a]D +13° (chloroform)
Absorption maximum: uv max: 239 nm (e 17540)
Therap-Cat: Progestogen; in treatment of prostatic hypertrophy.
Keywords: Antiprostatic Hypertrophy; Progestogen.

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