Glybuzole
Title: Glybuzole
CAS Registry Number: 1492-02-0
CAS Name: N-[5-(1,1-Dimethylethyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide
Additional Names: N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide; 2-benzenesulfonamido-5-tert-butyl-1,3,4-thiadiazole; desaglybuzole
Manufacturers' Codes: TH-1395; RP-7891; AN-1324
Trademarks: Gludiase (Bellon)
Molecular Formula: C12H15N3O2S2
Molecular Weight: 297.40
Percent Composition: C 48.46%, H 5.08%, N 14.13%, O 10.76%, S 21.56%
Literature References: Prepn: Macrae, Drain, GB 822947 (1959 to Smith & Nephew), C.A. 54, 4622h (1960); FR M3389 (1965 to Rhône-Poulenc), C.A. 64, 3553a (1966). Pharmacodynamics: Bargeton et al., Arch. Int. Pharmacodyn. 153, 379 (1965).
Properties: Needles, mp 163°.
Melting point: mp 163°
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Sulfonylurea Derivatives.

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