Homofenazine
Title: Homofenazine
CAS Registry Number: 3833-99-6
CAS Name: Hexahydro-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1H-1,4-diazepine-1-ethanol
Additional Names: 1-(b-hydroxyethyl)-4-[3-(2-trifluoromethylphenothiazin-10-yl)propyl]hexahydro-1,4-diazepine; 1-(2-hydroxyethyl)-4-[3-(3-trifluoromethylphenothiazin-10-yl)propyl]homopiperazine; 3-trifluoromethyl-10-[3-[4-(2-hydroxyethyl)homopiperazino]propyl]phenothiazine
Molecular Formula: C23H28F3N3OS
Molecular Weight: 451.55
Percent Composition: C 61.18%, H 6.25%, F 12.62%, N 9.31%, O 3.54%, S 7.10%
Literature References: Prepn: Schuler et al., US 3040043 (1962 to Degussa).
Properties: bp1 230-240°.
Boiling point: bp1 230-240°
 
Derivative Type: Dihydrochloride
CAS Registry Number: 1256-01-5
Trademarks: Pasaden (Asta)
Molecular Formula: C23H28F3N3OS.2HCl
Molecular Weight: 524.47
Percent Composition: C 52.67%, H 5.77%, F 10.87%, N 8.01%, O 3.05%, S 6.11%, Cl 13.52%
 
Derivative Type: Difumarate
CAS Registry Number: 3093-71-8
Molecular Formula: C23H28F3N3OS.2C4H4O4
Molecular Weight: 683.69
Percent Composition: C 54.46%, H 5.31%, F 8.34%, N 6.15%, O 21.06%, S 4.69%
Properties: Crystals, mp 148°.
Melting point: mp 148°
 
Therap-Cat: Sedative.
Keywords: Sedative/Hypnotic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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