Iodofenphos
Title: Iodofenphos
CAS Registry Number: 18181-70-9
CAS Name: Phosphorothioic acid O-(2,5-dichloro-4-iodophenyl) O,O-dimethyl ester
Additional Names: O-(2,5-dichloro-4-iodophenyl) O,O-dimethyl phosphorothioate
Manufacturers' Codes: C-9491
Trademarks: Nuvanol N (Novartis Agro)
Molecular Formula: C8H8Cl2IO3PS
Molecular Weight: 413.00
Percent Composition: C 23.27%, H 1.95%, Cl 17.17%, I 30.73%, O 11.62%, P 7.50%, S 7.76%
Literature References: Organophosphorous insecticide with stomach and contact activity. Prepn: E. Beriger et al., ZA 6506107; eidem, US 3468984 (1965, 1969 both to Ciba). Metabolism and anti-cholinesterase activity: F. R. Johannsen, C. O. Knowles, J. Econ. Entomol. 63, 693 (1970). GLC determn in cattle urine and tissues: M. C. Ivey, D. D. Oehler, J. Agric. Food Chem. 24, 1049 (1976). Crystal and molecular structure: R. G. Baughman, P.-J. Yu, ibid. 30, 293 (1982). Use to control flies and ticks in cattle: R. O. Drummond et al., J. Econ. Entomol. 65, 1354 (1972). Review: B. C. Haddow, T. G. Marks, Proc. 5th Br. Insectic. Fungic. Conf. 2, 531 (1970).
Properties: Pale yellow oil, solidifies to crystals, mp 72-73° (Beriger). Also reported as white crystals, mp 75° (Haddow). Sol in acetone, xylene. Slightly sol in alcohol. Soly in water: <2 ppm. LD50 in rats, female mice (mg/kg): 2100, >10000, orally (Haddow, Marks).
Melting point: mp 72-73° (Beriger); mp 75° (Haddow)
Toxicity data: LD50 in rats, female mice (mg/kg): 2100, >10000, orally (Haddow, Marks)
Use: Insecticide.
Therap-Cat-Vet: Ectoparasiticide.

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