Iomeglamic Acid
Title: Iomeglamic Acid
CAS Registry Number: 25827-76-3
CAS Name: 5-[(3-Amino-2,4,6-triiodophenyl)methylamino]-5-oxopentanoic acid
Additional Names: 3¢-amino-2¢,4¢,6¢-triiodo-N-methylglutaranilic acid; N-methyl-N-(3-amino-2,4,6-triiodophenyl)glutaramic acid; N-methyl-N-(2,4,6-triiodo-3-aminophenyl)glutaramidic acid
Manufacturers' Codes: RG-270
Trademarks: Falignost (Hexal)
Molecular Formula: C12H13I3N2O3
Molecular Weight: 613.96
Percent Composition: C 23.48%, H 2.13%, I 62.01%, N 4.56%, O 7.82%
Literature References: Prepn: Cassebaum, Dierbach, DD 67209 (1969), C.A. 72, 66654j (1970). Biotransformation: Pfeifer et al., Pharmazie 27, 403 (1972). Pharmacology: H. Bekker et al., ibid. 411. Clinical evaluation: Barke, Zentralbl. Pharm. Pharmakother. Laboratoriumsdiagn. 110, 1117 (1971).
Properties: Yellow to brown crystals from acetic acid, mp 169°. Freely sol in DMF; slightly sol in ethanol, chloroform. Practically insol in water. LD50 i.v. in mice: 500 mg/kg (Bekker).
Melting point: mp 169°
Toxicity data: LD50 i.v. in mice: 500 mg/kg (Bekker)
Therap-Cat: Diagnostic aid (radiopaque medium¾cholecystographic).
Keywords: Diagnostic Aid (Radiopaque Medium).

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