Isolan
Title: Isolan
CAS Registry Number: 119-38-0
CAS Name: Dimethylcarbamic acid 3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl ester
Additional Names: 1-isopropyl-3-methyl-5-pyrazolyl dimethylcarbamate
Manufacturers' Codes: G-23611
Molecular Formula: C10H17N3O2
Molecular Weight: 211.26
Percent Composition: C 56.85%, H 8.11%, N 19.89%, O 15.15%
Literature References: Carbamate insecticide: Gerguson, Alexander, J. Agric. Food Chem. 1, 288 (1953); Muller, Spindler, Experientia 10, 91 (1954). Prepd by treating the K salt of the enol form of 1-isopropyl-3-methyl-5-pyrazolone with dimethylcarbamoyl chloride: CH 279553 and CH 282655; GB 681376 (all 1952 to Geigy); Kost, Sagitullin, Zh. Obshch. Khim. 33, 867 (1963), C.A. 59, 8724 (1963). Toxicity studies: T. B. Gaines et al., Nature 209, 88 (1966); T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969).
Properties: Liquid, bp0.7 103°, bp2.5 117.5-118°. d 1.07. Vapor pressure at 20° = 0.001 mm Hg. Unlike most insecticides, Isolan is more toxic to rats dermally than orally (Gaines, 1966). LD50 in male, female rats (mg/kg): 23, 13 orally; 5.6, 6.2 dermally (Gaines, 1969).
Boiling point: bp0.7 103°; bp2.5 117.5-118°
Density: d 1.07
Toxicity data: LD50 in male, female rats (mg/kg): 23, 13 orally; 5.6, 6.2 dermally (Gaines, 1969)
Use: Insecticide.

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