Isoxaflutole
Title: Isoxaflutole
CAS Registry Number: 141112-29-0
CAS Name: (5-Cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone
Additional Names: 5-cyclopropyl-1,2-oxazol-4-yl a,a,a-trifluoro-2-mesyl-p-tolyl ketone; 5-cyclopropylisoxazol-4-yl 2-mesyl-4-trifluoromethylphenyl ketone; 5-cyclopropyl-4-(2-methanesulfonyl-4-trifluoromethylbenzoyl)isoxazole
Manufacturers' Codes: 264-EUP-99; RPA-201772
Trademarks: Balance (Bayer CropSci.); Merlin (Bayer CropSci.)
Molecular Formula: C15H12F3NO4S
Molecular Weight: 359.32
Percent Composition: C 50.14%, H 3.37%, F 15.86%, N 3.90%, O 17.81%, S 8.92%
Literature References: Pre-emergent herbicide designed for use in maize. Disrupts pigment biosynthesis via an inhibition of 4-hydroxyphenylpyruvate dioxygenase. Prepn: P. A. Cain et al., EP 527036 (1993 to Rhone-Poulenc). Properties and biological activity: B. M. Luscombe et al., Brighton Crop Prot. Conf. - Weeds 1995, 35. Weed control in maize: B. M. Luscombe, K. E. Pallett, Pestic. Outlook 7, 29 (1996). Mechanism of action: K. E. Pallett et al., Pestic. Sci. 50, 83 (1997). Soil persistence: J. Rouchaud et al., Bull. Environ. Contam. Toxicol. 60, 577 (1998).
Properties: Off-white or pale yellow solid, mp 138-138.5° (Cain); also reported as mp 140° (Luscombe). Vapor pressure at 25°: 1´10-6 Pa. Soly in water: 6.2 mg/l. LD50 in rats, quails, mallard ducks (mg/kg): >5000, >2150, >2150 orally; in rabbits (mg/kg): >2000 dermally (Luscombe).
Melting point: mp 138-138.5° (Cain); mp 140°
Toxicity data: LD50 in rats, quails, mallard ducks (mg/kg): >5000, >2150, >2150 orally; in rabbits (mg/kg): >2000 dermally (Luscombe)
Use: Herbicide.

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