Lauroguadine
Title: Lauroguadine
CAS Registry Number: 135-43-3
CAS Name: N,N¢¢¢-[4-(Dodecyloxy)-1,3-phenylene]bisguanidine
Additional Names: 1,1¢-[4-(dodecyloxy)-m-phenylene]diguanidine; 2,4-diguanidinophenyl lauryl ether; 2,4-diguanidino-1-dodecyloxybenzene; 2,4-diguanidino-1-lauryloxybenzene; 2,4-diguanidinophenyl dodecyl ether; dodecyl 2,4-diguanidinophenyl ether
Molecular Formula: C20H36N6O
Molecular Weight: 376.54
Percent Composition: C 63.80%, H 9.64%, N 22.32%, O 4.25%
Literature References: Prepn of the dihydrochloride: Pasini, Farmaco Ed. Sci. 8, 646 (1953); idem, Rend. Sci. Farmitalia 1, 405 (1954); GB 730394 (1955 to Farmitalia).
 
Derivative Type: Dihydrochloride monohydrate
Manufacturers' Codes: P-7
Trademarks: Farmidril (Farmitalia)
Molecular Formula: C20H36N6O.2HCl.H2O
Molecular Weight: 467.48
Percent Composition: C 51.38%, H 8.62%, N 17.98%, O 6.84%, Cl 15.17%
Properties: Crystals from water + ethanol. Sinters from 135-210°, dec 250°. Soly (g/100 ml): 0.2 in cold water; ~10 in boiling water; 84.2 in methanol (25°). Practically insol in acetone, benzene. Aq solns are neutral to litmus.
 
Therap-Cat: Antiprotozoal (Trichomonas).
Keywords: Antiprotozoal (Trichomonas).

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