Lufenuron
Title: Lufenuron
CAS Registry Number: 103055-07-8
CAS Name: N-[[[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluorobenzamide
Additional Names: 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea; fluphenacur
Manufacturers' Codes: CGA-184699
Trademarks: Program (Novartis)
Molecular Formula: C17H8Cl2F8N2O3
Molecular Weight: 511.15
Percent Composition: C 39.95%, H 1.58%, Cl 13.87%, F 29.73%, N 5.48%, O 9.39%
Literature References: Chitin synthesis inhibitor. Prepn: J. Drabek, M. Böger, EP 179022; eidem, US 4798837 (1986, 1989 both to Ciba-Geigy). Effect on fleas following oral administration in cats: W. F. Hink et al., J. Med. Entomol. 28, 424 (1991). HPLC determn: M. Zakson et al., Pestic. Sci. 35, 117 (1992). Review of properties and field trials in crops: F. Buholzer et al., Meded. Fac. Landbouwwet. Univ. Gent 57, 781-790 (1992).
Properties: Colorless, odorless, crystalline solid, mp 174.1°. Vapor pressure (25°): <4 ´ 10-6 Pa. Soly (20°): water <0.1 ppm; acetone 40%; cyclohexanone 35%; xylene 5%; methanol 4.5%. Log P (n-octanol/water): 5.12. LD50 in rats (mg/kg): >2000 orally; LC50 in rats (mg/m3): >2350 (Buholzer).
Melting point: mp 174.1°
Log P: Log P (n-octanol/water): 5.12
Toxicity data: LD50 in rats (mg/kg): >2000 orally; LC50 in rats (mg/m3): >2350 (Buholzer)
Therap-Cat-Vet: Ectoparasiticide.

Others monographs:
TEMPOCefaclorLonafarnib2-Nonyldioxolane
LysergamidePhosphinothricinZosuquidarEtofenprox
BitolterolCeftazidimeFluticasone PropionateCalcium Oxide
NicosulfuronBretylium TosylateTritolyl Phosphate2,4-Difluoroaniline
©2016 DrugLead US FDA&EMEA