Melanotan
Title: Melanotan
CAS Registry Number: 75921-69-6
CAS Name: 4-L-Norleucine-7-D-phenylalanine-a-melanotropin (swine)
Additional Names: [Nle4,D-Phe7]-a-MSH; melanotan-1
Molecular Formula: C78H111N21O19
Molecular Weight: 1646.85
Percent Composition: C 56.89%, H 6.79%, N 17.86%, O 18.46%
Literature References: Synthetic analog of human a-melanocyte-stimulating hormone, see MSH. Stimulates melanin production which protects skin from UV radiation. Prepn and bioactivity: T. K. Sawyer et al., Proc. Natl. Acad. Sci. USA 77, 5754 (1980); idem et al., J. Med. Chem. 25, 1022 (1982); V. J. Hruby et al., US 4457864 (1984 to University Patents). Review of pharmacology and development: M. E. Hadley et al., Pharmaceut. Biotechnol. 11, 575-595 (1998). Clinical induction of skin tanning: N. Levine et al., J. Am. Med. Assoc. 266, 2730 (1991); R. T. Dorr et al., Arch. Dermatol. 140, 827 (2004).
Therap-Cat: Prevention of sunburn injury.

Others monographs:
D-Mannitol HexanitrateStruvite4-Amino-3-phenylbutyric AcidNateglinide
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PropacetamolDiethyl Maleate3,3',4',5-TetrachlorosalicylanilideBlankophor® R
DulcinHistamineEthylestrenolAMPA
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