Methafurylene
Title: Methafurylene
CAS Registry Number: 531-06-6
CAS Name: N-(2-Furanylmethyl)-N¢,N¢-dimethyl-N-2-pyridinyl-1,2-ethanediamine
Additional Names: 2-[(2-dimethylaminoethyl)furfurylamino]pyridine; N,N-dimethyl-N¢-(2-pyridyl)-N¢-furfurylethylenediamine; N¢-(2-furylmethyl)-N¢-(2-pyridyl)-N,N-dimethylethylenediamine
Molecular Formula: C14H19N3O
Molecular Weight: 245.32
Percent Composition: C 68.54%, H 7.81%, N 17.13%, O 6.52%
Literature References: Prepn: Vaughan, Anderson, J. Am. Chem. Soc. 70, 2607 (1948); Kyrides, Zienty, ibid. 71, 1122 (1949); Horclois, US 2502151 (1950 to Rhône-Poulenc).
Properties: Light yellow oil, bp0.2 117.5-118°.
Boiling point: bp0.2 117.5-118°
 
Derivative Type: Hydrochloride
Molecular Formula: C14H19N3O.HCl
Molecular Weight: 281.78
Percent Composition: C 59.67%, H 7.15%, N 14.91%, O 5.68%, Cl 12.58%
Properties: Needles from ethyl acetate, mp 117-119°.
Melting point: mp 117-119°
 
Derivative Type: Dihydrogen citrate
Molecular Formula: C14H19N3O.C6H8O7
Molecular Weight: 437.44
Percent Composition: C 54.91%, H 6.22%, N 9.61%, O 29.26%
Properties: Crystals from methanol-ether or from methyl ethyl ketone, mp 95-97°.
Melting point: mp 95-97°
 
Derivative Type: Fumarate
CAS Registry Number: 5429-41-4
Manufacturers' Codes: F-151
Trademarks: Foralamin (Eaton)
Molecular Formula: C14H19N3O.C4H4O4
Molecular Weight: 361.39
Percent Composition: C 59.82%, H 6.41%, N 11.63%, O 22.14%
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Ethylenediamine Derivatives.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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