Methestrol
Title: Methestrol
CAS Registry Number: 130-73-4
CAS Name: 4,4¢-(1,2-Diethyl-1,2-ethanediyl)bis[2-methylphenol]
Additional Names: 4,4¢-(1,2-diethylethylene)di-o-cresol; 3,4-bis(3-methyl-4-hydroxyphenyl)hexane; dimethylhexestrol; promethestrol; g-promethestrol
Molecular Formula: C20H26O2
Molecular Weight: 298.42
Percent Composition: C 80.50%, H 8.78%, O 10.72%
Literature References: Prepd by hydrolysis of the dipropionate: Niederl et al., J. Am. Chem. Soc. 70, 508 (1948). Chromatographic identification and determn: R. W. Roos, J. Pharm. Sci. 63, 594 (1974). Pharmacologic study: P. H. Jellinck, A. M. Newcombe, Biochem. Pharmacol. 29, 3031 (1980). Pharmacotherapeutic study: C. B. Hammond, W. S. Maxson, Fertil. Steril. 37, 5 (1982).
Properties: Crystals from dil acetic acid, mp 145°.
Melting point: mp 145°
 
Derivative Type: Dipropionate
Trademarks: Meprane Dipropionate (Reed & Carnrick)
Molecular Formula: C26H34O4
Molecular Weight: 410.55
Percent Composition: C 76.06%, H 8.35%, O 15.59%
Properties: Cryst, mp 115°. Freely sol in ether, ethyl acetate, benzene; slightly sol in alc. Practically insol in water, dil acids.
Melting point: mp 115°
 
Therap-Cat: Estrogen.
Keywords: Estrogen; Nonsteroidal.

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