Methscopolamine Bromide
Title: Methscopolamine Bromide
CAS Registry Number: 155-41-9
CAS Name: (1a,2b,4b,5a,7b)-7-[(2S)-3-Hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide
Additional Names: 6b,7b-epoxy-3a-hydroxy-8-methyl-1aH,5aH-tropanium bromide tropate (ester); N-methylscopolammonium bromide; hyoscine methyl bromide; scopolamine methobromide; scopolamine methyl bromide; epoxymethamine bromide
Trademarks: Holopon (Altana); Pamine (Bradley)
Molecular Formula: C18H24BrNO4
Molecular Weight: 398.29
Percent Composition: C 54.28%, H 6.07%, Br 20.06%, N 3.52%, O 16.07%
Literature References: Anticholinergic. Prepd by the action of methyl bromide on scopolamine base: Visscher, US 2753288 (1956 to Upjohn). Treatment of duodenal ulcer by transdermally administered methscopolamine bromide: R. P. Walt et al., Br. Med. J. 284, 1736 (1982).
Properties: Crystals from ethanol, dec 214-217°. Freely sol in water, in dil ethanol. Slightly sol in abs ethanol.
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic; Antimuscarinic.

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