Molindone
Title: Molindone
CAS Registry Number: 7416-34-4
CAS Name: 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one
Additional Names: 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)indol-4(5H)-one
Molecular Formula: C16H24N2O2
Molecular Weight: 276.37
Percent Composition: C 69.53%, H 8.75%, N 10.14%, O 11.58%
Literature References: Prepn: BE 670798; I. J. Pachter, K. Schoen, US 3491093 (1966, 1970 both to Endo). Pharmacology: Sugerman, Herrmann, Clin. Pharmacol. Ther. 8, 261 (1967); Claghorn, Curr. Ther. Res. 11, 524 (1969); Guerrero-Figueroa et al., ibid. 15, 508 (1973). Toxicity study: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Crystals, mp 180-181°.
Melting point: mp 180-181°
 
Derivative Type: Hydrochloride
CAS Registry Number: 15622-65-8
Manufacturers' Codes: EN-1733A
Trademarks: Lidone (Abbott); Moban (Endo)
Properties: LD50 orally in rats: 261 mg/kg (Goldenthal).
Toxicity data: LD50 orally in rats: 261 mg/kg (Goldenthal)
 
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic.

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