Monocrotophos
Title: Monocrotophos
CAS Registry Number: 6923-22-4
CAS Name: (E)-Phosphoric acid dimethyl [1-methyl-3-(methylamino)-3-oxo-1-propenyl] ester
Additional Names: (E)-phosphoric acid dimethyl ester, ester with 3-hydroxy-N-methylcrotonamide; 3-(dimethoxyphosphinyloxy)-N-methyl-cis-crotonamide; dimethyl 2-methylcarbamoyl-1-methylvinyl phosphate; dimethyl phosphate of 3-hydroxy-N-methyl-cis-crotonamide
Manufacturers' Codes: C-1414; ENT-27129; SD-9129
Trademarks: Phoskill (United Phosphorus)
Molecular Formula: C7H14NO5P
Molecular Weight: 223.16
Percent Composition: C 37.67%, H 6.32%, N 6.28%, O 35.85%, P 13.88%
Literature References: General prepn: Whetstone, Stiles, US 2802855; see also Ward, Morales, US 3400177 (1957, 1968 both to Shell). Metabolite of dicrotophos, q.v.: Menzer, Casida, J. Agric. Food Chem. 13, 102 (1965). Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969).
Properties: Crystals, mp 54-55°. Commercial product is a reddish-brown solid, mp 25-30°. Vapor pressure at 20°: 7 ´ 106 mm Hg. Misc with water; sol in acetone, ethanol. Practically insol in diesel oils, kerosine. LD50 in male, female rats (mg/kg): 17, 20 orally; 126, 112 dermally (Gaines).
Melting point: mp 54-55°; mp 25-30°
Toxicity data: LD50 in male, female rats (mg/kg): 17, 20 orally; 126, 112 dermally (Gaines)
CAUTION: Potential symptoms of overexposure are eye irritation, miosis, blurred vision; dizziness, convulsions; dyspnea; salivation, abdominal cramps, nausea, diarrhea, vomiting. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 218.
Use: Insecticide.

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