Mopidamol
Title: Mopidamol
CAS Registry Number: 13665-88-8
CAS Name: 2,2¢,2¢¢,2¢¢¢-[[4-(1-Piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol
Additional Names: 2,2¢,2¢¢,2¢¢¢-[(4-piperidinopyrimido[5,4-d]-pyrimidine-2,6-diyl)dinitrilo]tetraethanol; 2,6-bis(diethanolamino)-4-piperidinopyrimido[5,4-d]pyrimidine
Manufacturers' Codes: RA-233
Trademarks: Rapenton (Thomae)
Molecular Formula: C19H31N7O4
Molecular Weight: 421.49
Percent Composition: C 54.14%, H 7.41%, N 23.26%, O 15.18%
Literature References: An inhibitor of platelet aggregation with antimetastatic properties. Prepn: GB 1051218 corresp to J. Roch, H. Scheffler, US 3322755 (1966, 1967 both to Boehringer, Ing.). Effect on tumor cell metastasis: J. L. Ambrus et al., J. Med. 9, 183 (1978); on inhibition of adenosine uptake into platelets: J. P. Lips et al., Biochem. Pharmacol. 29, 43 (1980). Therapeutic use: R. L. Clark, Cancer 43, 790 (1979); I. L. Bonta et al., Agents Actions Suppl. 4, 278 (1979).
Properties: Deep yellow crystals, mp 157-158°.
Melting point: mp 157-158°
Therap-Cat: Antineoplastic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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