Nicametate
Title: Nicametate
CAS Registry Number: 3099-52-3
CAS Name: 3-Pyridinecarboxylic acid 2-(diethylamino)ethyl ester
Additional Names: nicotinic acid 2-diethylaminoethyl ester; diethylaminoethyl 3-pyridinecarboxylate; diethylaminoethyl nicotinate
Trademarks: Eucast
Molecular Formula: C12H18N2O2
Molecular Weight: 222.28
Percent Composition: C 64.84%, H 8.16%, N 12.60%, O 14.40%
Literature References: Prepd from nicotinoyl chloride and diethylaminoethanol or from nicotinic acid and diethylaminoethyl chloride: Blicke, Jenner, J. Am. Chem. Soc. 64, 1722 (1942). Clinical trial in vascular pathology: P. Langeron, J. Sci. Med. Lille 90, 179 (1972). Use of the citrate in cardiovascular surgery: C. Stankowiak et al., Lille Med. 18, 1039 (1973).
Properties: Liquid. bp10 155-157°; bp2 120-125°.
Boiling point: bp10 155-157°; bp2 120-125°
 
Derivative Type: Hydrochloride
CAS Registry Number: 56676-64-3
Molecular Formula: C12H18N2O2.HCl
Molecular Weight: 258.74
Percent Composition: C 55.70%, H 7.40%, N 10.83%, O 12.37%, Cl 13.70%
Properties: Crystals from acetone, ethanol or isopropyl alcohol, mp 128-129°.
Melting point: mp 128-129°
 
Derivative Type: Citrate monohydrate
Trademarks: Euclidan; Nutrin (Chemipharm); Soclidan
Molecular Formula: C12H18N2O2.C6H8O7.H2O
Molecular Weight: 432.42
Percent Composition: C 50.00%, H 6.53%, N 6.48%, O 37.00%
 
Therap-Cat: Vasodilator (cerebral, peripheral).
Keywords: Vasodilator (Cerebral); Vasodilator (Peripheral).
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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