Nifurtoinol
Title: Nifurtoinol
CAS Registry Number: 1088-92-2
CAS Name: 3-(Hydroxymethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione
Additional Names: 3-(hydroxymethyl)-1-[(5-nitrofurfurylidene)amino]hydantoin; 1-[(5-nitrofurfurylidene)amino]-3-(hydroxymethyl)hydantoin
Trademarks: Urfadyn (Zambon)
Molecular Formula: C9H8N4O6
Molecular Weight: 268.18
Percent Composition: C 40.31%, H 3.01%, N 20.89%, O 35.80%
Literature References: Prepn: Michels, BE 611941 corresp to US 3446802 (1962, 1969 to Norwich Pharmacal); Spencer, Michels, J. Org. Chem. 29, 3416 (1964).
Properties: Yellow crystals from aq formaldehyde. When heated on a melting-point block, loses formaldehyde, then further decomposes at same temp as nitrofurantoin. uv max (2% in dimethylformamide): 367.5, 265 nm (e 17900, 12800).
Absorption maximum: uv max (2% in dimethylformamide): 367.5, 265 nm (e 17900, 12800)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Nitrofurans.

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