Octodrine
Title: Octodrine
CAS Registry Number: 543-82-8
CAS Name: 6-Methyl-2-heptanamine
Additional Names: 6-methyl-2-heptylamine; 2-methyl-6-aminoheptane; 6-amino-2-methylheptane; 2-amino-6-methylheptane; a,e-dimethylhexylamine; 1,5-dimethylhexylamine
Manufacturers' Codes: SKF-51
Trademarks: Vaporpac (Menley & James)
Molecular Formula: C8H19N
Molecular Weight: 129.24
Percent Composition: C 74.35%, H 14.82%, N 10.84%
Literature References: a-Adrenergic agonist. Prepd from the corresponding saturated ketone: Rohrmann, Shonle, J. Am. Chem. Soc. 66, 1516 (1944). Pharmacology: E. J. Fellows, J. Pharmacol. Exp. Ther. 90, 351 (1947).
 
Derivative Type: dl-Form
Properties: Viscous liquid, fishy odor, bp 154-156°. nD24 1.4200.
Boiling point: bp 154-156°
Index of refraction: nD24 1.4200
 
Derivative Type: Hydrochloride
Molecular Formula: C8H19N.HCl
Molecular Weight: 165.70
Percent Composition: C 57.99%, H 12.17%, N 8.45%, Cl 21.40%
Properties: Crystals, sol in water. LD50 in mice, rats (mg/kg): 59, 41.5 i.p. (Fellows).
Toxicity data: LD50 in mice, rats (mg/kg): 59, 41.5 i.p. (Fellows)
 
Derivative Type: Sulfate
Molecular Formula: (C8H19N)2.H2SO4
Molecular Weight: 356.56
Percent Composition: C 53.90%, H 11.31%, N 7.86%, S 8.99%, O 17.95%
Properties: Crystals, sol in water.
 
Therap-Cat: Decongestant.
Keywords: a-Adrenergic Agonist; Decongestant.

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